Hemagglutinin 222 Variants in Pandemic (H1N1) 2009 Virus

نویسندگان

  • Maria Beatrice Valli
  • Marina Selleri
  • Silvia Meschi
  • Paola Zaccaro
  • Donatella Vincenti
  • Eleonora Lalle
  • Maria Rosaria Capobianchi
  • Stefano Menzo
چکیده

reported. Badgers and binturong have been housed in zoological gardens for decades without incidence of infl uenza. Increased surveillance for infl uenza by the scientifi c community during the pandemic may have resulted in the novel recognition of infection in these species. Alternatively, the current pandemic (H1N1) 2009 virus may have a broader host range and stronger virulence than viruses in the past. Pandemic (H1N1) 2009 was fi rst detected in humans in March 2009 and reached pandemic levels by June of that year, rapidly establishing a rich pool for the development of genetic variants. Naturally acquired disease has now been described in 10 animal species, and experimental infection has been reported in an additional 2 animals (mice and cynomolgus macaques) (9). The ubiquity of pandemic (H1N1) 2009 and its ability to infect a diverse range of hosts is worrisome for the health of wildlife and for the possibility of creating additional reservoirs that could alter the evolution of subtype H1N1 viruses by applying varied selection pressures and establishing new ways of generating unique reassortant strains.

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عنوان ژورنال:

دوره 17  شماره 

صفحات  -

تاریخ انتشار 2011